Relevance of the Hygiene Hypothesis to Early vs. Late Onset Allergic Rhinitis
نویسندگان
چکیده
منابع مشابه
Relevance of the hygiene hypothesis to early vs. late onset allergic rhinitis.
INTRODUCTION The hygiene hypothesis proposes that reduced exposure to infections in early life increases the risk of developing allergic conditions including allergic rhinitis. We examined the association between markers of the hygiene hypothesis and allergic rhinitis that developed before 7 years of age and allergic rhinitis that developed after 7 years of age. METHODS The Tasmanian Longitud...
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Background Inverse associations between allergic disease and having pets or siblings are commonly attributed to the hygiene hypothesis. As an extension, one could posit that a less diverse gut microbiome in the infant, also linked with the development of allergic disease, would be a function of fewer microbes in the home environment. Piglet studies, however, indicate that greater microbe divers...
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ژورنال
عنوان ژورنال: Pediatrics
سال: 2009
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.2009-1870k